Embedding siRNA sequences targeting Apolipoprotein B100 in shRNA and miRNA scaffolds results in differential processing and in vivo efficacy-Reference-Cited by-同舟云学术

Embedding siRNA sequences targeting Apolipoprotein B100 in shRNA and miRNA scaffolds results in differential processing and in vivo efficacy

Published:2013-01 Issue:1 Volume:21 Page:217-227
ISSN:1525-0016
Container-title:Molecular Therapy
language:en
Short-container-title:Molecular Therapy

Author:

Maczuga Piotr,Lubelski Jacek,van Logtenstein Richard,Borel Florie,Blits Bas,Fakkert Erwin,Costessi Adalberto,Butler Derek,van Deventer Sander,Petry Harald,Koornneef Annemart,Konstantinova Pavlina

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology,Genetics,Molecular Biology,Molecular Medicine

Reference52 articles.

1. MicroRNA function: multiple mechanisms for a tiny RNA?;Pillai;RNA,2005

2. Animal MicroRNAs confer robustness to gene expression and have a significant impact on 3'UTR evolution;Stark;Cell,2005

3. The promises and pitfalls of RNA-interference-based therapeutics;Castanotto;Nature,2009

4. When cellular networks run out of control: global dysregulation of the RNAi machinery in human pathology and therapy;Mockenhaupt;Prog Mol Biol Transl Sci,2011

5. Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha;Zeng;EMBO J,2005

Cited by 22 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Engineering strategies to safely drive CAR T-cells into the future;Frontiers in Immunology;2024-06-19

2. Efficient shRNA-based knockdown of multiple target genes for cell therapy using a chimeric miRNA cluster platform;Molecular Therapy - Nucleic Acids;2023-12

3. Broadening the Horizons of RNA Delivery Strategies in Cancer Therapy;Bioengineering;2022-10-19

4. Efficient and Precise Processing of the Optimized Primary Artificial MicroRNA in a Huntingtin-Lowering Adeno-Associated Viral Gene Therapy In Vitro and in Mice and Nonhuman Primates;Human Gene Therapy;2022-01-01

5. Disruption of adenosine 2A receptor improves the anti-tumor function of anti-mesothelin CAR T cells both in vitro and in vivo;Experimental Cell Research;2021-12