Potent and Selective Agonism of the Melanocortin Receptor 4 With MK-0493 Does Not Induce Weight Loss in Obese Human Subjects: Energy Intake Predicts Lack of Weight Loss Efficacy-Reference-Cited by-同舟云学术

Potent and Selective Agonism of the Melanocortin Receptor 4 With MK-0493 Does Not Induce Weight Loss in Obese Human Subjects: Energy Intake Predicts Lack of Weight Loss Efficacy

Published:2009-09-09 Issue:6 Volume:86 Page:659-666
ISSN:0009-9236
Container-title:Clinical Pharmacology & Therapeutics
language:
Short-container-title:Clin Pharmacol Ther

Author:

Krishna R,Gumbiner B,Stevens C,Musser B,Mallick M,Suryawanshi S,Maganti L,Zhu H,Han T H,Scherer L,Simpson B,Cosgrove D,Gottesdiener K,Amatruda J,Rolls B J,Blundell J,Bray G A,Fujioka K,Heymsfield S B,Wagner J A,Herman G A

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology

Reference24 articles.

1. Targeting melanocortin receptors: an approach to treat weight disorders and sexual dysfunction

2. Melanocortin-4 Receptor (MC4R) Agonists for the Treatment of Obesity

3. Obesity-associated mutations in the melanocortin 4 receptor provide novel insights into its function

4. A missense mutation disrupting a dibasic prohormone processing site in pro-opiomelanocortin (POMC) increases susceptibility to early-onset obesity through a novel molecular mechanism

5. Targeted Disruption of the Melanocortin-4 Receptor Results in Obesity in Mice

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