Blocking negative effects of senescence in human skin fibroblasts with a plant extract
Author:
Publisher
Springer Science and Business Media LLC
Subject
Geriatrics and Gerontology,Aging
Link
http://www.nature.com/articles/s41514-018-0023-5.pdf
Reference53 articles.
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2. Baker, D. J. et al. Naturally occurring p16 Ink4a-positive cells shorten healthy lifespan. Nature 1–20. https://doi.org/10.1038/nature16932 (2016).
3. Demaria, M. et al. An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA. Dev. Cell 31, 722–733 (2014).
4. Krtolica, A., Parrinello, S., Lockett, S., Desprez, P. Y. & Campisi, J. Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging. Proc. Natl. Acad. Sci. USA 98, 12072–12077 (2001).
5. Acosta, J. C. et al. A complex secretory program orchestrated by the inflammasome controls paracrine senescence. Nat. Cell Biol. 15, 978–990 (2013).
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