p38α suppresses normal and cancer cell proliferation by antagonizing the JNK

p38α suppresses normal and cancer cell proliferation by antagonizing the JNK–c-Jun pathway

Published:2007-04-29 Issue:6 Volume:39 Page:741-749
ISSN:1061-4036
Container-title:Nature Genetics
language:en
Short-container-title:Nat Genet

Author:

Hui Lijian,Bakiri Latifa,Mairhorfer Andreas,Schweifer Norbert,Haslinger Christian,Kenner Lukas,Komnenovic Vukoslav,Scheuch Harald,Beug Hartmut,Wagner Erwin F

Publisher

Springer Science and Business Media LLC

Subject

Genetics

Link

http://www.nature.com/articles/ng2033.pdf

Reference43 articles.

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3. Bulavin, D.V. & Fornace, A.J. Jr. p38 MAP kinase's emerging role as a tumor suppressor. Adv. Cancer Res. 92, 95–118 (2004).

4. Lavoie, J.N., L'Allemain, G., Brunet, A., Muller, R. & Pouyssegur, J. Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway. J. Biol. Chem. 271, 20608–20616 (1996).

5. Bulavin, D.V., Kovalsky, O., Hollander, M.C. & Fornace, A.J. Jr. Loss of oncogenic H-ras-induced cell cycle arrest and p38 mitogen-activated protein kinase activation by disruption of Gadd45a. Mol. Cell. Biol. 23, 3859–3871 (2003).

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