Pyrrocidine A, a metabolite of endophytic fungi, has a potent apoptosis-inducing activity against HL60 cells through caspase activation via the Michael addition-Reference-Cited by-同舟云学术

Pyrrocidine A, a metabolite of endophytic fungi, has a potent apoptosis-inducing activity against HL60 cells through caspase activation via the Michael addition

Published:2015-10-28 Issue:3 Volume:69 Page:133-140
ISSN:0021-8820
Container-title:The Journal of Antibiotics
language:en
Short-container-title:J Antibiot

Author:

Uesugi Shota,Fujisawa Nozomi,Yoshida Jun,Watanabe Mitsuru,Dan Shingo,Yamori Takao,Shiono Yoshihito,Kimura Ken-ichi

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Pharmacology

Link

http://www.nature.com/articles/ja2015103.pdf

Reference34 articles.

1. Koehn, F. E. & Carter, G. T. The evolving role of natural products in drug discovery. Nat. Rev. Drug Discov. 4, 206–220 (2005).

2. Drahl, C., Cravatt, B. F. & Sorensen, E. J. Protein-reactive natural products. Angew. Chem. Int. Ed. 44, 5788–5809 (2005).

3. Selim, K. A., E.-Beih, A. A., A.-Rahman, T. M. & E.-Diwany, A. I. Biology of endophytic fungi. Curr. Res. Environ. Appl. Mycol. 2, 31–82 (2012).

4. Gunatilaka, A. A. Natural products from plant-associated microorganisms: distribution, structural diversity, bioactivity, and implications of their occurrence. J. Nat. Prod. 69, 509–526 (2006).

5. Debbab, A., Aly, A. H. & Proksch, P. Bioactive secondary metabolites from endophytes and associated marine derived fungi. Fungal Divers. 49, 1–12 (2011).

Cited by 28 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Tracking Inhibition of Human Small C-Terminal Domain Phosphatase 1 Using 193 nm Ultraviolet Photodissociation Mass Spectrometry;Journal of the American Society for Mass Spectrometry;2024-04-25

2. Metabolic Investigation and Auxiliary Enzyme Modelization of the Pyrrocidine Pathway Allow Rationalization of Paracyclophane-Decahydrofluorene Formation;ACS Chemical Biology;2024-04-05

3. Fungal Enzyme Inhibitors: Potent Repository of Lead Compounds to Curb Cancer;Fungi Bioactive Metabolites;2024

4. Graphene oxide and modified graphene oxide-mediated synthesis of medicinally active compounds;Green Approaches in Medicinal Chemistry for Sustainable Drug Design;2024

5. Ascomylactam C Induces an Immunogenic Cell Death Signature via Mitochondria-Associated ER Stress in Lung Cancer and Melanoma;Marine Drugs;2023-11-21