Interaction between ubiquitin–protein ligase SCFSKP2 and E2F-1 underlies the regulation of E2F-1 degradation
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology
Link
http://www.nature.com/articles/ncb0599_14.pdf
Reference45 articles.
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3. Leone, G. et al. E2F-3 activity is regulated during the cell cycle and is required for the induction of S phase. Genes Dev. 12, 2120–2130 (1998).
4. Campanero, M. R. & Flemington, E. K. Regulation of E2F through ubiquitin-proteasome-dependent degradation: stabilization by the pRB tumor suppressor protein. Proc. Natl Acad. Sci. USA 94, 2221–2226 (1997).
5. Hofmann, F., Martelli, F., Livingston, D. M. & Wang, Z. The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway. Genes Dev. 10, 2949– 2959 (1996).
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