Ras inhibitor farnesylthiosalicylic acid conjugated with IR783 dye exhibits improved tumor-targeting and altered anti-breast cancer mechanisms in mice-Reference-Cited by-同舟云学术

Ras inhibitor farnesylthiosalicylic acid conjugated with IR783 dye exhibits improved tumor-targeting and altered anti-breast cancer mechanisms in mice

Published:2021-11-29 Issue: Volume: Page:
ISSN:1671-4083
Container-title:Acta Pharmacologica Sinica
language:en
Short-container-title:Acta Pharmacol Sin

Author:

Huang Qiu-ju,Liao Guo-chao,Zhuang Xue-rong,Yang Meng-lan,Yao Jing-jing,Deng Jian-hua,Zhang Yan-min,Wang Ying,Qi Xiao-xiao,Pan Dong-feng,Guan Yang,Huang Zhi-ying,Zhang Feng-xue,Liu Zhong-qiu,Lu Lin-lin

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,General Medicine

Link

https://www.nature.com/articles/s41401-021-00775-5.pdf

Reference38 articles.

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3. Kwong LN, Costello JC, Liu H, Jiang S, Helms TL, Langsdorf AE, et al. Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma. Nat Med. 2012;18:1503–10.

4. Ledford H. Cancer: the Ras renaissance. Nature. 2015;520:278–80.

5. Laheru D, Shah P, Rajeshkumar NV, McAllister F, Taylor G, Goldsweig H, et al. Integrated preclinical and clinical development of S-trans, trans-Farnesylthiosalicylic Acid (FTS, Salirasib) in pancreatic cancer. Invest N Drugs. 2012;30:2391–9.

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