Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma-Reference-Cited by-同舟云学术

Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma

Published:2012-09-16 Issue:10 Volume:18 Page:1503-1510
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Kwong Lawrence N,Costello James C,Liu Huiyun,Jiang Shan,Helms Timothy L,Langsdorf Aliete E,Jakubosky David,Genovese Giannicola,Muller Florian L,Jeong Joseph H,Bender Ryan P,Chu Gerald C,Flaherty Keith T,Wargo Jennifer A,Collins James J,Chin Lynda

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm.2941.pdf

Reference45 articles.

1. Schubbert, S., Shannon, K. & Bollag, G. Hyperactive Ras in developmental disorders and cancer. Nat. Rev. CancerNatl. Rev. 7, 295–308 (2007).

2. Jakob, J.A. et al. NRAS mutation status is an independent prognostic factor in metastatic melanoma. Cancer 118, 4013–4023 (2011).

3. Flaherty, K.T. et al. Inhibition of mutated, activated BRAF in metastatic melanoma. N. Engl. J. Med. 363, 809–819 (2010).

4. Gilmartin, A.G. et al. GSK1120212 (JTP-74057) is an inhibitor of MEK activity and activation with favorable pharmacokinetic properties for sustained in vivo pathway inhibition. Clin. Cancer Res. 17, 989–1000 (2011).

5. Bollag, G. et al. Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma. Nature 467, 596–599 (2010).

Cited by 311 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Cyclin-dependent kinase 4 drives cystic kidney disease in the absence of mTORC1 signaling activity;Kidney International;2024-08

2. O-GlcNAcylation of MITF regulates its activity and CDK4/6 inhibitor resistance in breast cancer;Nature Communications;2024-07-03

3. Potential role of cyclin-dependent kinase 4/6 inhibitors in the treatment of mucosal melanoma;Holistic Integrative Oncology;2024-05-28

4. A Gold Standard-Derived Modular Barcoding Approach to Cancer Transcriptomics;Cancers;2024-05-15

5. Synergistic induction of autophagy in gastric cancer by targeting CDK4/6 and MEK through AMPK/mTOR pathway;Heliyon;2024-05