Leflunomide increased the renal exposure of acyclovir by inhibiting OAT1/3 and MRP2-Reference-Cited by-同舟云学术

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Leflunomide increased the renal exposure of acyclovir by inhibiting OAT1/3 and MRP2

Published:2019-07-24 Issue:1 Volume:41 Page:129-137
ISSN:1671-4083
Container-title:Acta Pharmacologica Sinica
language:en
Short-container-title:Acta Pharmacol Sin

Author:

Liao Xiao-ying,Deng Qiang-qiang,Han Li,Wu Zhi-tao,Peng Zhao-liang,Xie Yuan,Wang Guang-ji,Aa Ji-ye,Pan Guo-yu

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,General Medicine

Link

http://www.nature.com/articles/s41401-019-0283-z.pdf

Reference50 articles.

1. Smolen JS, Landewe R, Bijlsma J, Burmester G, Chatzidionysiou K, Dougados M, et al. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update. Ann Rheum Dis. 2017;76:960–77.

2. Rozman. Clinical pharmacokinetics of leflunomide. Clin Pharmacokinet. 2002;41:421–30.

3. Kalgutkar AS, Nguyen HT, Vaz ADN, Doan A, Dalvie DK, McLeod DG, et al. In vitro metabolism studies on the isoxazole ring scission in the anti-inflammatory agent lefluonomide to its active alpha-cyanoenol metabolite A771726. Drug Metab Dispos. 2003;31:1240–50.

4. Wang L, Ma LL, Lin Y, Liu X, Xiao L, Zhang Y, et al. Leflunomide increases hepatic exposure to methotrexate and its metabolite by differentially regulating multidrug resistance-associated protein Mrp2/3/4 transporters via peroxisome proliferator-activated receptor alpha activation. Mol Pharmacol. 2018;93:563–74.

5. Ueo H, Motohashi H, Katsura T, Inui K. Human organic anion transporter hOAT3 is a potent transporter of cephalosporin antibiotics, in comparison with hOAT1. Biochem Pharmacol. 2005;70:1104–13.

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