LGR5 expression is regulated by EGF in early colorectal adenomas and governs EGFR inhibitor sensitivity
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Oncology
Link
http://www.nature.com/articles/bjc2017412.pdf
Reference43 articles.
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3. Baker AM, Graham TA, Elia G, Wright NA, Rodriguez-Justo M (2015) Characterization of LGR5 stem cells in colorectal adenomas and carcinomas. Sci Rep 5: 8654.
4. Barker N, van Es JH, Kuipers J, Kujala P, van den Born M, Cozijnsen M, Haegebarth A, Korving J, Begthel H, Peters PJ, Clevers H (2007) Identification of stem cells in small intestine and colon by marker gene Lgr5. Nature 449 (7165): 1003–1007.
5. Basak O, Beumer J, Wiebrands K, Seno H, van Oudenaarden A, Clevers H (2017) Induced quiescence of Lgr5+ stem cells in intestinal organoids enables differentiation of hormone-producing enteroendocrine cells. Cell Stem cell 20 (2): 177–190 e4.
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