Characterization of LGR5 stem cells in colorectal adenomas and carcinomas
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/srep08654.pdf
Reference36 articles.
1. Barker, N. et al. Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro. Cell Stem Cell 6, 25–36 (2010).
2. Barker, N. et al. Identification of stem cells in small intestine and colon by marker gene Lgr5. Nature 449, 1003–7 (2007).
3. Leedham, S. J. et al. A basal gradient of Wnt and stem-cell number influences regional tumour distribution in human and mouse intestinal tracts. Gut 62, 83–93 (2013).
4. Ziskin, J. L. et al. In situ validation of an intestinal stem cell signature in colorectal cancer. Gut 62, 1012–23 (2013).
5. Merlos-Suarez, A. et al. The intestinal stem cell signature identifies colorectal cancer stem cells and predicts disease relapse. Cell Stem Cell 8, 511–24 (2011).
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