PIN1, the cell cycle and cancer
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Earth and Planetary Sciences,General Environmental Science
Link
http://www.nature.com/articles/nrc2107.pdf
Reference94 articles.
1. Galat, A. Peptidylprolyl cis/trans isomerases (immunophilins): biological diversity—targets—functions. Curr. Top. Med. Chem. 3, 1315–1347 (2003).
2. Lu, K. P. et al. Targeting carcinogenesis: a role for the prolyl isomerase Pin1? Mol. Carcinog. 45, 397–402 (2006).
3. Pastorino, L. et al. The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-β production. Nature 440, 528–534 (2006).
4. Lu, K. P., Hanes, S. D. & Hunter, T. A human peptidyl-prolyl isomerase essential for regulation of mitosis. Nature 380, 544–547 (1996). PIN1 is identified and described for the first time in mammals as a NIMA-interacting protein with a potential role as a negative regulator of mitosis.
5. Hanes, S. D., Shank, P. R. & Bostian, K. A. Sequence and mutational analysis of ESS1, a gene essential for growth in Saccharomyces cerevisiae. Yeast 5, 55–72 (1989). ESS1P, the yeast PIN1 homologue, is described as an essential protein in yeast, a fact that did not hold true in mammalian systems.
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