A mouse model for embryonal tumors with multilayered rosettes uncovers the therapeutic potential of Sonic-hedgehog inhibitors-Reference-Cited by-同舟云学术

A mouse model for embryonal tumors with multilayered rosettes uncovers the therapeutic potential of Sonic-hedgehog inhibitors

Published:2017-09-11 Issue:10 Volume:23 Page:1191-1202
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Neumann Julia E,Wefers Annika K,Lambo Sander,Bianchi Edoardo,Bockstaller Marie,Dorostkar Mario M,Meister Valerie,Schindler Pia,Korshunov Andrey,von Hoff Katja,Nowak Johannes,Warmuth-Metz Monika,Schneider Marlon R,Renner-Müller Ingrid,Merk Daniel J,Shakarami Mehdi,Sharma Tanvi,Chavez Lukas,Glass Rainer,Chan Jennifer A,Taketo M Mark,Neumann Philipp,Kool Marcel,Schüller Ulrich

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm.4402.pdf

Reference71 articles.

1. Li, M. et al. Frequent amplification of a chr19q13.41 microRNA polycistron in aggressive primitive neuroectodermal brain tumors. Cancer Cell 16, 533–546 (2009).

2. Spence, T. et al. CNS-PNETs with C19MC amplification and/or LIN28 expression comprise a distinct histogenetic diagnostic and therapeutic entity. Acta Neuropathol. 128, 291–303 (2014).

3. Korshunov, A. et al. Focal genomic amplification at 19q13.42 comprises a powerful diagnostic marker for embryonal tumors with ependymoblastic rosettes. Acta Neuropathol. 120, 253–260 (2010).

4. Korshunov, A. et al. LIN28A immunoreactivity is a potent diagnostic marker of embryonal tumor with multilayered rosettes (ETMR). Acta Neuropathol. 124, 875–881 (2012).

5. Kleinman, C.L. et al. Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor ETMR. Nat. Genet. 46, 39–44 (2014).

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