Lipid metabolism offers anticancer treatment by regulating ferroptosis
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology
Link
http://www.nature.com/articles/s41418-019-0418-2.pdf
Reference15 articles.
1. Tesfay L, Paul BT, Konstorum A, Deng Z, Cox AO, Lee J, et al. Steroyl-CoA Desaturase 1 (SCD1) protects ovarian cancer cells from ferroptotic cell death. Cancer Res. 2019. https://doi.org/10.1158/0008-5472.CAN-19-0369 . [Epub ahead of print]
2. Pisanu ME, Noto A, De Vitis C, Morrone S, Scognamiglio G, Botti G, et al. Blockade of Stearoyl-CoA-desaturase 1 activity reverts resistance to cisplatin in lung cancer stem cells. Cancer Lett. 2017;406:93–104. https://doi.org/10.1016/j.canlet.2017.07.027
3. Noto A, De Vitis C, Pisanu ME, Roscilli G, Ricci G, Catizone A, et al. Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ. Oncogene. 2017;36:4671–2. https://doi.org/10.1038/onc.2017.212
4. Tracz-Gaszewska Z, Dobrzyn P. Stearoyl-CoA desaturase 1 as a therapeutic target for the treatment of cancer. Cancers (Basel). 2019;11:E948. https://doi.org/10.3390/cancers11070948
5. Dixon SJ, Stockwell BR. The hallmarks of ferroptosis. Annu Rev Cancer Biol. 2019;3:35–54.
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