Associations of CYP3A4, NR1I2, CYP2C19 and P2RY12 polymorphisms with clopidogrel resistance in Chinese patients with ischemic stroke-Reference-Cited by-同舟云学术

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Associations of CYP3A4, NR1I2, CYP2C19 and P2RY12 polymorphisms with clopidogrel resistance in Chinese patients with ischemic stroke

Published:2016-05-02 Issue:7 Volume:37 Page:882-888
ISSN:1671-4083
Container-title:Acta Pharmacologica Sinica
language:en
Short-container-title:Acta Pharmacol Sin

Author:

Liu Rui,Zhou Zi-yi,Chen Yi-bei,Li Jia-li,Yu Wei-bang,Chen Xin-meng,Zhao Min,Zhao Yuan-qi,Cai Ye-feng,Jin Jing,Huang Min

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,General Medicine

Link

http://www.nature.com/articles/aps201641.pdf

Reference47 articles.

1. Kelly RP, Close SL, Farid NA, Witers KJ, Shen L, Natanegara F, et al. Pharmacokinetics and pharmacodynamics following maintenance doses of prasugrel and clopidogrel in Chinese carriers of CYP2C19 variants. Br J Clin Pharmacol 2012; 73: 93–105.

2. Boggon R, van Staa TP, Timmis A, Hemingway H, Ray KK, Begg A, et al. Clopidogrel discontinuation after acute coronary syndromes: frequency, predictors and associations with death and myocardial infarction — a hospital registry - primary care linked cohort (MINAP-GPRD). Eur Heart J 2011; 32: 2376–86.

3. Perry CG, Shuldiner AR . Pharmacogenomics of anti-platelet therapy: how much evidence is enough for clinical implementation? J Hum Genet 2013; 58: 339–45.

4. Nguyen TA, Diodati JG, Pharand C . Resistance to clopidogrel: a review of the evidence. J Am Coll Cardiol 2005; 45: 1157–64.

5. Serebruany VL, Steinhubl SR, Berger PB, Malinin AI, Bhatt DL, Topol EJ . Variability in platelet responsiveness to clopidogrel among 544 individuals. J Am Coll Cardiol 2005; 45: 246–51.

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