Pharmacogenomics of anti-platelet therapy: how much evidence is enough for clinical implementation?

Author:

Perry Christina G,Shuldiner Alan R

Publisher

Springer Science and Business Media LLC

Subject

Genetics(clinical),Genetics

Reference78 articles.

1. Kushner, F. G., Hand, M., Smith, S. C. Jr, King, S. B. 3rd, Anderson, J. L., Antman, E. M. et al. 2009 focused updates: ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction (updating the 2004 guideline and 2007 focused update) and ACC/AHA/SCAI guidelines on percutaneous coronary intervention (updating the 2005 guideline and 2007 focused update), a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J. Am. Coll. Cardiol. 54, 2205–2241 (2009).

2. Anderson, J. L., Adams, C. D., Antman, E. M., Bridges, C. R., Califf, R. M., Casey, D. E. Jr et al. ACC/AHA 2007 guidelines for the management of patients with unstable angina/non ST-elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines for the Management of Patients With Unstable Angina/Non ST-Elevation Myocardial Infarction): developed in collaboration with the American College of Emergency Physicians, the Society for Cardiovascular Angiography and Interventions, and the Society of Thoracic Surgeons: endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation and the Society for Academic Emergency Medicine. Circulation 116, e148–e304 (2007).

3. Mega, J. L., Close, S. L., Wiviott, S. D., Shen, L., Walker, J. R., Simon, T. et al. Genetic variants in ABCB1 and CYP2C19 and cardiovascular outcomes after treatment with clopidogrel and prasugrel in the TRITON-TIMI 38 trial: a pharmacogenetic analysis. Lancet 376, 1312–1319 (2010).

4. Fisch, A. S., Perry, C. G., Stephens, S. H., Horenstein, R. B. & Shuldiner, A. R. Pharmacogenomics of anti-platelet and anti-coagulation therapy. Curr. Cardiol. Reports; in press (2013).

5. Ancrenaz, V., Daali, Y., Fontana, P., Besson, M., Samer, C., Dayer, P. et al. Impact of genetic polymorphisms and drug-drug interactions on clopidogrel and prasugrel response variability. Curr. Drug Metab. 11, 667–677 (2010).

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