A toolbox for the longitudinal assessment of healthspan in aging mice-Reference-Cited by-同舟云学术

A toolbox for the longitudinal assessment of healthspan in aging mice

Published:2020-01-08 Issue:2 Volume:15 Page:540-574
ISSN:1754-2189
Container-title:Nature Protocols
language:en
Short-container-title:Nat Protoc

Author:

Bellantuono I.^ORCID,de Cabo R.,Ehninger D.,Di Germanio C.^ORCID,Lawrie A.^ORCID,Miller J.,Mitchell S. J.,Navas-Enamorado I.,Potter P. K.,Tchkonia T.,Trejo J. L.^ORCID,Lamming D. W.^ORCID

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology

Link

http://www.nature.com/articles/s41596-019-0256-1.pdf

Reference134 articles.

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2. Tchkonia, T. & Kirkland, J. L. Aging, cell senescence, and chronic disease: emerging therapeutic strategies. JAMA 320, 1319–1320 (2018).

3. Martin-Montalvo, A. et al. Metformin improves healthspan and lifespan in mice. Nat. Commun. 4, 2192 (2013).

4. Neff, F. et al. Rapamycin extends murine lifespan but has limited effects on aging. J. Clin. Invest. 123, 3272–3291 (2013).

5. Zhu, Y. et al. The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs. Aging Cell 14, 644–658 (2015).

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