The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs

Author:

Zhu Yi1,Tchkonia Tamara1,Pirtskhalava Tamar1,Gower Adam C.2,Ding Husheng1,Giorgadze Nino1,Palmer Allyson K.1,Ikeno Yuji34,Hubbard Gene B.34,Lenburg Marc2,O'Hara Steven P.1,LaRusso Nicholas F.1,Miller Jordan D.1,Roos Carolyn M.1,Verzosa Grace C.1,LeBrasseur Nathan K.1,Wren Jonathan D.5,Farr Joshua N.1,Khosla Sundeep1,Stout Michael B.1,McGowan Sara J.6,Fuhrmann‐Stroissnigg Heike6,Gurkar Aditi U.6,Zhao Jing6,Colangelo Debora6,Dorronsoro Akaitz6,Ling Yuan Yuan6,Barghouthy Amira S.6,Navarro Diana C.6,Sano Tokio6,Robbins Paul D.6,Niedernhofer Laura J.6,Kirkland James L.1

Affiliation:

1. Robert and Arlene Kogod Center on Aging Mayo Clinic Rochester MN USA

2. Section of Computational Biomedicine Boston University School of Medicine Boston MA USA

3. Departments of Pathology Barshop Institute for Longevity and Aging Studies The University of Texas Health Science Center San Antonio TX USA

4. Research Service Geriatric Research and Education Clinical Center Audie L. Murphy VA Hospital South Texas Veterans Health Care System San Antonio TX USA

5. Department of Biochemistry and Molecular Biology Oklahoma Medical Research Foundation Oklahoma City OK USA

6. Department of Metabolism and Aging The Scripps Research Institute Jupiter FL USA

Funder

National Institutes of Health

Glenn Foundation for Medical Research

Ted Nash Long Life Foundation

Publisher

Wiley

Subject

Cell Biology,Aging

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