SIRT6 regulates SREBP1c-induced glucolipid metabolism in liver and pancreas via the AMPKα-mTORC1 pathway
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology,Pathology and Forensic Medicine
Link
https://www.nature.com/articles/s41374-021-00715-1.pdf
Reference39 articles.
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2. Priest, C. & Tontonoz, P. Inter-organ cross-talk in metabolic syndrome. Nat. Metab. 1, 1177–1188 (2019).
3. Li, J. et al. Sirt6 opposes glycochenodeoxycholate-induced apoptosis of biliary epithelial cells through the AMPK/PGC-1alpha pathway. Cell Biosci. 10, 43 (2020).
4. Elhanati, S. et al. Multiple regulatory layers of SREBP1/2 by SIRT6. Cell Rep. 4, 905–912 (2013).
5. Cui, X. et al. SIRT6 regulates metabolic homeostasis in skeletal muscle through activation of AMPK. Am. J. Physiol. Endocrinol. Metab. 313, E493–E505 (2017).
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