Sustained hedgehog signaling in medulloblastoma tumoroids is attributed to stromal astrocytes and astrocyte-derived extracellular matrix
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology,Pathology and Forensic Medicine
Link
http://www.nature.com/articles/s41374-020-0443-2.pdf
Reference53 articles.
1. Lee RT, Zhao Z, Ingham PW. Hedgehog signalling. Development. 2016;143:367–72.
2. Ingham PW, McMahon AP. Hedgehog signaling in animal development: paradigms and principles. Genes Dev. 2001;15:3059–87.
3. Rohatgi R, Milenkovic L, Corcoran RB, Scott MP. Hedgehog signal transduction by Smoothened: pharmacologic evidence for a 2-step activation process. Proc Natl Acad Sci USA. 2009;106:3196–201.
4. Northcott PA, Korshunov A, Pfister SM, Taylor MD. The clinical implications of medulloblastoma subgroups. Nat Rev Neurol. 2012;8:340–51.
5. Liu Y, Yuelling LW, Wang Y, Du F, Gordon RE, O’Brien JA, et al. Astrocytes promote medulloblastoma progression through hedgehog secretion. Cancer Res. 2017;77:6692–703.
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