Hedgehog signal transduction by Smoothened: Pharmacologic evidence for a 2-step activation process
Author:
Publisher
Proceedings of the National Academy of Sciences
Subject
Multidisciplinary
Reference22 articles.
1. Targeting the Hedgehog pathway in cancer
2. Shifting paradigms in Hedgehog signaling
3. The dynamics of the cycle
4. Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine
5. Hedgehog regulates smoothened activity by inducing a conformational switch
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3. Hedgehog signaling in tissue homeostasis, cancers, and targeted therapies;Signal Transduction and Targeted Therapy;2023-08-18
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