pRAD50: a novel and clinically applicable pharmacodynamic biomarker of both ATM and ATR inhibition identified using mass spectrometry and immunohistochemistry-Reference-Cited by-同舟云学术

pRAD50: a novel and clinically applicable pharmacodynamic biomarker of both ATM and ATR inhibition identified using mass spectrometry and immunohistochemistry

Published:2018-11 Issue:10 Volume:119 Page:1233-1243
ISSN:0007-0920
Container-title:British Journal of Cancer
language:en
Short-container-title:Br J Cancer

Author:

Jones Gemma N.,Rooney Claire,Griffin Nicola,Roudier Martine,Young Lucy A.,Garcia-Trinidad Antonio,Hughes Gareth D.,Whiteaker Jeffrey R.,Wilson Zena,Odedra Rajesh,Zhao Lei,Ivey Richard G.,Howat William J.,Harrington Elizabeth A.,Barrett J. Carl,Ramos-Montoya Antonio,Lau Alan,Paulovich Amanda G.,Cadogan Elaine B.,Pierce Andrew J.

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Link

http://www.nature.com/articles/s41416-018-0286-4.pdf

Reference53 articles.

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3. Paull, T. T. Mechanisms of ATM Activation. Annu. Rev. Biochem. 84, 711–738 (2015).

4. Shiloh, Y. ATM and related protein kinases: safeguarding genome integrity. Nat. Rev. Cancer 3, 155–168 (2003).

5. Uziel, T. et al. Requirement of the MRN complex for ATM activation by DNA damage. EMBO J. 22, 5612–5621 (2003).

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