Mechanistic study of the retro-aza-Michael reaction in saccharothriolide L: identification of 2-amino-4-methylphenol as an effective protecting tool for the Michael acceptor
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Publisher
Springer Science and Business Media LLC
Link
https://www.nature.com/articles/s41429-024-00741-3.pdf
Reference14 articles.
1. Rudolf GC, Koch MF, Mandl FA, Sieber SA. Subclass-specific labeling of protein-reactive natural products with customized nucleophilic probes. Chemistry. 2015;21:3701–7.
2. Duplan V, et al. Synthesis of sesquiterpene-inspired derivatives designed for covalent binding and their inhibition of the NF-κB pathway. Org Biomol Chem. 2014;12:370–5.
3. Zhao Q, Cong Y. Michael reaction acceptor molecules in chemical biology. Prog Chem. 2007;19:1972–6.
4. Kakeya H. Natural products-prompted chemical biology: phenotypic screening and a new platform for target identification. Nat Prod Rep. 2016;33:648–54.
5. Powers JC, Asgian JL, Ekici OD, James KE. Irreversible inhibitors of serine, cysteine, and threonine proteases. Chem Rev. 2002;102:4639–750.
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