TP0586532, a non-hydroxamate LpxC inhibitor, reduces LPS release and IL-6 production both in vitro and in vivo
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology
Link
https://www.nature.com/articles/s41429-021-00498-z.pdf
Reference44 articles.
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4. Oda S, Hirasawa H, Shiga H, Nakanishi K, Matsuda K, Nakamua M. Sequential measurement of IL-6 blood levels in patients with systemic inflammatory response syndrome (SIRS)/sepsis. Cytokine 2005;29:169–75.
5. Kirikae T, Kirikae F, Saito S, Tominaga K, Tamura H, Uemura Y, et al. Biological characterization of endotoxins released from antibiotic-treated Pseudomonas aeruginosa and Escherichia coli. Antimicrob Agents Chemother. 1998;42:1015–21.
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