Semi-synthesis and structure-activity relationship study yield antibacterial vicenistatin derivatives with low cytotoxicity
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology
Link
https://www.nature.com/articles/s41429-023-00701-3.pdf
Reference22 articles.
1. Shindo K, Kamishohara M, Odagawa A, Matsuoka M, Kawai H. Vicenistatin, a novel 20-membered macrocyclic lactam antitumor antibiotic. J Antibiot. 1993;46:1076–81.
2. Matsushima Y, Itoh H, Eguchi T, Kakinuma K. Enantioselective and convergent synthesis of the 20-membered lactam aglycon of vicenistatin antitumor antibiotic. J Antibiot. 1998;51:688–91.
3. Matsushima Y, Itoh H, Nakayama T, Horiuchi S, Eguchi T, Kakinuma K. Enantioselective total synthesis of vicenistatin, a novel 20-membered macrocyclic lactam antitumor antibiotic. J Chem Soc, Perkin Trans 1. 2002;7:949–58.
4. Fukuda H, Nakamura S, Eguchi T, Iwabuchi Y, Kanoh N. Concise total synthesis of vicenistatin. Synlett. 2010;17:2589–92.
5. Fukuda H, Nishiyama Y, Nakamura S, Ohno Y, Eguchi T, Iwabuchi Y, Usui T, Kanoh N. Synthesis and structure–activity relationship of vicenistatin, a cytotoxic 20‐membered macrolactam glycoside. Chem Asian J. 2012;7:2872–81.
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