Cytotoxic anthracycline and antibacterial tirandamycin analogues from a marine-derived Streptomyces sp. SCSIO 41399
Author:
Funder
National Natural Science Foundation of China
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology
Link
http://www.nature.com/articles/s41429-018-0103-6.pdf
Reference13 articles.
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2. Gui C, Mo XH, Gu YC, Ju JH. Elucidating the sugar tailoring steps in the cytorhodin biosynthetic pathway. Org Lett. 2017;19:5617–20.
3. Sann CL. Maleimide spacers as versatile linkers in the synthesis of bioconjugates of anthracyclines. Nat Prod Rep. 2006;23:357–67.
4. Royles BJL. Naturally occurring tetramic acids: structure, isolation, and synthesis. Chem Rev. 1995;95:1981–2001.
5. Mo XH, Huang HB, Ma JY, Wang ZW, Wang B, Zhang S, et al. Characterization of TrdL as a 10-hydroxy dehydrogenase and generation of new analogues from a tirandamycin biosynthetic pathway. Org Lett. 2011;13:2212–5.
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