Costunolide and dehydrocostuslactone combination treatment inhibit breast cancer by inducing cell cycle arrest and apoptosis through c-Myc/p53 and AKT/14-3-3 pathway
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/srep41254.pdf
Reference60 articles.
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2. Peng, Z. X., Wang, Y., Gu, X., Guo, X. J. & Yan, C. Study on the pharmacokinetics andmetabolism of costunolide and dehydrocostus lactone in rats by HPLC-UV and UPLC-Q-TOF/MS. Biomed. Chromatogr. 28, 1325–1334 (2014).
3. Peng, Z. X. et al. Metabolic transformation of breast cancer in a MCF-7 xenograft mouse model and inhibitory effect of volatile oil from Saussurea lappa Decne treatment. Metabolomics 11, 636–656 (2015).
4. Peng, Z. X., Wang, Y., Gu, X., Wen, Y. Y. & Yan, C. A platform for fast screening potential anti-breast cancer compounds in traditional Chinese medicines. Biomed. Chromatogr. 27, 1759–1766 (2013).
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