Systemic Administration of AAV8-α-galactosidase A Induces Humoral Tolerance in Nonhuman Primates Despite Low Hepatic Expression-Reference-Cited by-同舟云学术

Systemic Administration of AAV8-α-galactosidase A Induces Humoral Tolerance in Nonhuman Primates Despite Low Hepatic Expression

Published:2011-11 Issue:11 Volume:19 Page:1999-2011
ISSN:1525-0016
Container-title:Molecular Therapy
language:en
Short-container-title:Molecular Therapy

Author:

Nietupski Jennifer B,Hurlbut Gregory D,Ziegler Robin J,Chu Qiuming,Hodges Bradley L,Ashe Karen M,Bree Mark,Cheng Seng H,Gregory Richard J,Marshall John,Scheule Ronald K

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology,Genetics,Molecular Biology,Molecular Medicine

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3. Modulation of tolerance to the transgene product in a nonhuman primate model of AAV-mediated gene transfer to liver;Mingozzi;Blood,2007

4. Induction and role of regulatory CD4+CD25+ T cells in tolerance to the transgene product following hepatic in vivo gene transfer;Cao;Blood,2007

5. Factors influencing the development of an anti-factor IX (FIX) immune response following administration of adeno-associated virus-FIX;Ge;Blood,2001

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