Preclinical Safety of RNAi-Mediated HTT Suppression in the Rhesus Macaque as a Potential Therapy for Huntington's Disease-Reference-Cited by-同舟云学术

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Preclinical Safety of RNAi-Mediated HTT Suppression in the Rhesus Macaque as a Potential Therapy for Huntington's Disease

Published:2011-12 Issue:12 Volume:19 Page:2152-2162
ISSN:1525-0016
Container-title:Molecular Therapy
language:en
Short-container-title:Molecular Therapy

Author:

McBride Jodi L,Pitzer Mark R,Boudreau Ryan L,Dufour Brett,Hobbs Theodore,Ojeda Sergio R,Davidson Beverly L

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology,Genetics,Molecular Biology,Molecular Medicine

Reference48 articles.

1. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group;Huntington Disease Collaborative Research Group;Cell,1993

2. Neuropathological classification of Huntington's disease;Vonsattel;J Neuropathol Exp Neurol,1985

3. Role of basal ganglia in limb movements;DeLong;Hum Neurobiol,1984

4. Organization of striatopallidal, striatonigral, and nigrostriatal projections in the macaque;Hedreen;J Comp Neurol,1991

5. Differential activation of the caudate nucleus in primates performing spatial and nonspatial working memory tasks;Levy;J Neurosci,1997

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