TnpB homologues exapted from transposons are RNA-guided transcription factors
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Publisher
Springer Science and Business Media LLC
Link
https://www.nature.com/articles/s41586-024-07598-4.pdf
Reference111 articles.
1. Altae-Tran, H. et al. The widespread IS200/IS605 transposon family encodes diverse programmable RNA-guided endonucleases. Science 374, 57–65 (2021).
2. Karvelis, T. et al. Transposon-associated TnpB is a programmable RNA-guided DNA endonuclease. Nature 599, 692–696 (2021).
3. Meers, C. et al. Transposon-encoded nucleases use guide RNAs to promote their selfish spread. Nature 622, 863–871 (2023).
4. Zedaveinyte, R. et al. Antagonistic conflict between transposon-encoded introns and guide RNAs. Preprint at bioRxiv https://doi.org/10.1101/2023.11.20.567912 (2023).
5. Kapitonov, V. V., Makarova, K. S. & Koonin, E. V. ISC, a novel group of bacterial and archaeal DNA transposons that encode Cas9 homologs. J. Bacteriol. 198, 797–807 (2015).
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