A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1-Reference-Cited by-同舟云学术

A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1

Published:2019-05 Issue:7758 Volume:569 Page:718-722
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Zhao Baoyu,Du Fenglei,Xu Pengbiao,Shu Chang,Sankaran Banumathi,Bell Samantha L.,Liu Mengmeng,Lei Yuanjiu,Gao Xinsheng,Fu Xiaofeng,Zhu Fanxiu,Liu Yang,Laganowsky Arthur,Zheng Xueyun,Ji Jun-Yuan,West A. Phillip,Watson Robert O.,Li Pingwei

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41586-019-1228-x.pdf

Reference30 articles.

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2. Roers, A., Hiller, B. & Hornung, V. Recognition of endogenous nucleic acids by the innate immune system. Immunity 44, 739–754 (2016).

3. Barber, G. N. Innate immune DNA sensing pathways: STING, AIMII and the regulation of interferon production and inflammatory responses. Curr. Opin. Immunol. 23, 10–20 (2011).

4. Kato, H., Takahasi, K. & Fujita, T. RIG-I-like receptors: cytoplasmic sensors for non-self RNA. Immunol. Rev. 243, 91–98 (2011).

5. Paludan, S. R. & Bowie, A. G. Immune sensing of DNA. Immunity 38, 870–880 (2013).

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