CRISPR screens unveil signal hubs for nutrient licensing of T cell immunity-Reference-Cited by-同舟云学术

CRISPR screens unveil signal hubs for nutrient licensing of T cell immunity

Published:2021-11-18 Issue:7888 Volume:600 Page:308-313
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Long Lingyun,Wei Jun,Lim Seon Ah,Raynor Jana L.,Shi Hao^ORCID,Connelly Jon P.^ORCID,Wang Hong^ORCID,Guy Cliff,Xie Boer,Chapman Nicole M.,Fu Guotong,Wang Yanyan,Huang Hongling,Su Wei,Saravia Jordy^ORCID,Risch Isabel^ORCID,Wang Yong-Dong^ORCID,Li Yuxin^ORCID,Niu Mingming,Dhungana Yogesh,KC Anil,Zhou Peipei,Vogel Peter^ORCID,Yu Jiyang^ORCID,Pruett-Miller Shondra M.^ORCID,Peng Junmin^ORCID,Chi Hongbo^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

https://www.nature.com/articles/s41586-021-04109-7.pdf

Reference58 articles.

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2. Kim, J. & Guan, K. L. mTOR as a central hub of nutrient signalling and cell growth. Nat. Cell Biol. 21, 63–71 (2019).

3. Liu, G. Y. & Sabatini, D. M. mTOR at the nexus of nutrition, growth, ageing and disease. Nat. Rev. Mol. Cell Biol. 21, 183–203 (2020).

4. Huang, H., Long, L., Zhou, P., Chapman, N. M. & Chi, H. mTOR signaling at the crossroads of environmental signals and T-cell fate decisions. Immunol. Rev. 295, 15–38 (2020).

5. Shi, H. et al. Amino acids license kinase mTORC1 activity and Treg cell function via small G proteins Rag and Rheb. Immunity 51, 1012–1027 (2019).

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