Dietary modifications for enhanced cancer therapy
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41586-020-2124-0.pdf
Reference147 articles.
1. Sullivan, M. R. et al. Quantification of microenvironmental metabolites in murine cancers reveals determinants of tumor nutrient availability. eLife 8, e44235 (2019).
2. Cantor, J. R. et al. Physiologic medium rewires cellular metabolism and reveals uric acid as an endogenous inhibitor of UMP synthase. Cell 169, 258–272.e217 (2017).
3. Muir, A. et al. Environmental cystine drives glutamine anaplerosis and sensitizes cancer cells to glutaminase inhibition. eLife 6, e27713 (2017).
4. Davidson, S. M. et al. Environment impacts the metabolic dependencies of Ras-driven non-small cell lung cancer. Cell Metab. 23, 517–528 (2016).
5. Torrence, M. E. & Manning, B. D. Nutrient sensing in cancer. Annu. Rev. Cancer Biol. 2, 251–269 (2018). This review addresses a topic (not discussed here) that is key for understanding the consequences of dietary modifications that change nutrient availability at the tumour microenvironment, such as the dietary modifications listed above.
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