Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP Synthase-Reference-Cited by-同舟云学术

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Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP Synthase

Published:2017-04 Issue:2 Volume:169 Page:258-272.e17
ISSN:0092-8674
Container-title:Cell
language:en
Short-container-title:Cell

Author:

Cantor Jason R.,Abu-Remaileh Monther,Kanarek Naama,Freinkman Elizaveta,Gao Xin,Louissaint Abner,Lewis Caroline A.,Sabatini David M.

Funder

NIH

Koch Institute

Department of Defense

American Cancer Society

EMBO

AACR

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology

Reference85 articles.

1. Oxidative damage to DNA: relation to species metabolic rate and life span;Adelman;Proc. Natl. Acad. Sci. USA,1988

2. Uric acid and evolution;Álvarez-Lario;Rheumatology (Oxford),2010

3. The energy charge of the adenylate pool as a regulatory parameter. Interaction with feedback modifiers;Atkinson;Biochemistry,1968

4. Orotic aciduria and uridine monophosphate synthase: a reappraisal;Bailey;J. Inherit. Metab. Dis.,2009

5. Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides;Birsoy;Nature,2014

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