Neurotoxic reactive astrocytes induce cell death via saturated lipids-Reference-Cited by-同舟云学术

Neurotoxic reactive astrocytes induce cell death via saturated lipids

Published:2021-10-06 Issue:7883 Volume:599 Page:102-107
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Guttenplan Kevin A.^ORCID,Weigel Maya K.,Prakash Priya^ORCID,Wijewardhane Prageeth R.^ORCID,Hasel Philip^ORCID,Rufen-Blanchette Uriel,Münch Alexandra E.^ORCID,Blum Jacob A.,Fine Jonathan,Neal Mikaela C.,Bruce Kimberley D.,Gitler Aaron D.^ORCID,Chopra Gaurav^ORCID,Liddelow Shane A.^ORCID,Barres Ben A.

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

https://www.nature.com/articles/s41586-021-03960-y.pdf

Reference38 articles.

1. Liddelow, S. A. & Barres, B. A. Reactive astrocytes: production, function, and therapeutic potential. Immunity 46, 957–967 (2017).

2. Liddelow, S. A. et al. Neurotoxic reactive astrocytes are induced by activated microglia. Nature 541, 481–487 (2017).

3. Guttenplan, K. A. et al. Neurotoxic reactive astrocytes drive neuronal death after retinal injury. Cell Rep. 31, 107776 (2020).

4. Guttenplan, K. A. et al. Knockout of reactive astrocyte activating factors slows disease progression in an ALS mouse model. Nat. Commun. 11, 3753 (2020).

5. Nagai, M. et al. Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons. Nat. Neurosci. 10, 615–622 (2007).

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