Plasma membrane V-ATPase controls oncogenic RAS-induced macropinocytosis
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41586-019-1831-x.pdf
Reference37 articles.
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2. Kamphorst, J. J. et al. Human pancreatic cancer tumors are nutrient poor and tumor cells actively scavenge extracellular protein. Cancer Res. 75, 544–553 (2015).
3. Fennell, M., Commisso, C., Ramirez, C., Garippa, R. & Bar-Sagi, D. High-content, full genome siRNA screen for regulators of oncogenic HRAS-driven macropinocytosis. Assay Drug Dev. Technol. 13, 347–355 (2015).
4. Stransky, L., Cotter, K. & Forgac, M. The function of v-ATPases in cancer. Physiol. Rev. 96, 1071–1091 (2016).
5. Furuchi, T., Aikawa, K., Arai, H. & Inoue, K. Bafilomycin A1, a specific inhibitor of vacuolar-type H+-ATPase, blocks lysosomal cholesterol trafficking in macrophages. J. Biol. Chem. 268, 27345–27348 (1993).
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