RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6-Reference-Cited by-同舟云学术

RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6

Published:2018-05 Issue:7706 Volume:557 Page:564-569
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Szenker-Ravi Emmanuelle,Altunoglu Umut,Leushacke Marc,Bosso-Lefèvre Célia,Khatoo Muznah,Thi Tran Hong,Naert Thomas,Noelanders Rivka,Hajamohideen Amin,Beneteau Claire,de Sousa Sergio B.,Karaman Birsen,Latypova Xenia,Başaran Seher,Yücel Esra Börklü,Tan Thong Teck,Vlaminck Lena,Nayak Shalini S.,Shukla Anju,Girisha Katta Mohan,Le Caignec Cédric,Soshnikova Natalia,Uyguner Zehra Oya,Vleminckx Kris,Barker Nick,Kayserili Hülya,Reversade Bruno

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41586-018-0118-y.pdf

Reference44 articles.

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2. Glinka, A. et al. LGR4 and LGR5 are R-spondin receptors mediating Wnt/β-catenin and Wnt/PCP signalling. EMBO Rep. 12, 1055–1061 (2011).

3. Carmon, K. S., Gong, X., Lin, Q., Thomas, A. & Liu, Q. R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/β-catenin signaling. Proc. Natl Acad. Sci. USA 108, 11452–11457 (2011).

4. Niswander, L. Pattern formation: old models out on a limb. Nat. Rev. Genet. 4, 133–143 (2003).

5. Niemann, S. et al. Homozygous WNT3 mutation causes tetra-amelia in a large consanguineous family. Am. J. Hum. Genet. 74, 558–563 (2004).

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