LGR4 and LGR5 are R‐spondin receptors mediating Wnt/β‐catenin and Wnt/PCP signalling-Reference-Cited by-同舟云学术

LGR4 and LGR5 are R‐spondin receptors mediating Wnt/β‐catenin and Wnt/PCP signalling

Published:2011-10 Issue:10 Volume:12 Page:1055-1061
ISSN:1469-221X
Container-title:EMBO reports
language:en
Short-container-title:EMBO Rep

Author:

Glinka Andrei¹,Dolde Christine¹,Kirsch Nadine¹,Huang Ya‐Lin¹,Kazanskaya Olga¹,Ingelfinger Dierk²,Boutros Michael²,Cruciat Cristina‐Maria¹,Niehrs Christof¹³

Affiliation:

1. Division of Molecular Embryology, DKFZ‐‐ZMBH Alliance, DKFZ Im Neuenheimer Feld 580 Heidelberg D‐69120 Germany

2. Division of Signalling and Functional Genomics, DKFZ and University of Heidelberg Im Neuenheimer Feld 580 Heidelberg D‐69120 Germany

3. Institute of Molecular Biology Mainz 55128 Germany

Publisher

EMBO

Subject

Genetics,Molecular Biology,Biochemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1038/embor.2011.175

Reference25 articles.

1. R-spondin3 is required for mouse placental development

2. Leucine-Rich Repeat-Containing G-Protein-Coupled Receptors as Markers of Adult Stem Cells

3. R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6

4. The gene encoding R-spondin 4 (RSPO4), a secreted protein implicated in Wnt signaling, is mutated in inherited anonychia

5. R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/ -catenin signaling

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