Synthesis of portimines reveals the basis of their anti-cancer activity-Reference-Cited by-同舟云学术

Synthesis of portimines reveals the basis of their anti-cancer activity

Published:2023-09-20 Issue:7983 Volume:622 Page:507-513
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Tang Junchen^ORCID,Li Weichao^ORCID,Chiu Tzu-Yuan^ORCID,Martínez-Peña Francisco^ORCID,Luo Zengwei,Chong Christine T.^ORCID,Wei Qijia,Gazaniga Nathalia,West Thomas J.,See Yi Yang,Lairson Luke L.^ORCID,Parker Christopher G.^ORCID,Baran Phil S.^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

https://www.nature.com/articles/s41586-023-06535-1.pdf

Reference53 articles.

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2. Molgó, J. et al. Cyclic imine toxins from dinoflagellates: a growing family of potent antagonists of the nicotinic acetylcholine receptors. J. Neurochem. 142, 41–51 (2017).

3. Selwood, A. I. et al. Portimine: a bioactive metabolite from the benthic dinoflagellate Vulcanodinium rugosum. Tetrahedron Lett. 54, 4705–4707 (2013).

4. Cuddihy, S. L. et al. The marine cytotoxin portimine is a potent and selective inducer of apoptosis. Apoptosis 21, 1447–1452 (2016).

5. Jørgensen, L. et al. 14-Step synthesis of (+)-ingenol from (+)-3-carene. Science 341, 878–882 (2013).

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