The MDM2 RING-finger domain is required to promote p53 nuclear export
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology
Link
http://www.nature.com/articles/ncb0900_569.pdf
Reference27 articles.
1. Haupt, Y., Maya, R., Kazaz, A. & Oren, M. Mdm2 promotes the rapid degradation of p53. Nature 387, 296–299 (1997).
2. Kubbutat, M. H., Jones, S. N. & Vousden, K. H. Regulation of p53 stability by MDM2. Nature 387, 299–303 (1997).
3. Kudo, N. et al. Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1. Exp. Cell Res. 242, 540–547 (1998).
4. Freedman, D. A. & Levine, A. J. Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6. Mol. Cell Biol. 18, 7288–7293 (1998).
5. Stommel, J. M. et al. A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking. EMBO J. 18, 1660–1672 (1999).
Cited by 314 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. MYC Oncogene: A Druggable Target for Treating Cancers with Natural Products;Aging and disease;2024
2. Dihydropyrimidine derivatives as MDM2 inhibitors;Chemical Biology & Drug Design;2023-11-27
3. Repression of rRNA gene transcription by endothelial SPEN deficiency normalizes tumor vasculature via nucleolar stress;Journal of Clinical Investigation;2023-10-16
4. Prion protein-dependent regulation of p53-MDM2 crosstalk during endoplasmic reticulum stress and doxorubicin treatments might be essential for cell fate in human breast cancer cell line, MCF-7;Experimental Cell Research;2023-08
5. C9orf72 poly‐PR helps p53 escape from the ubiquitin‐proteasome system and promotes its stability;Journal of Neurochemistry;2023-06-15
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3