Skin micro-organs from several frog species secrete a repertoire of powerful antimicrobials in culture
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology
Link
http://www.nature.com/articles/ja201250.pdf
Reference26 articles.
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3. Rollins-Smith, L. A., Reinert, L. K., Miera, V. & Conlon, J. M. Antimicrobial peptide defenses of the Tarahumara frog, Rana tarahumarae. Biochem. Biophys. Res. Commun. 297, 361–367 (2002).
4. Vanhoye, D., Bruston, F., Nicolas, P. & Amiche, M. Antimicrobial peptides from hylid and ranin frogs originated from a 150 million years old ancestral precursors with a conserved signal peptide but a hypermutable antimicrobial domain. Eur. J. Biochem. 270, 2068–2081 (2003).
5. Conlon, J. M., Al-Ghaferi, N., Abraham, B. & Leprince, J. Strategies for development of naturally-occurring antimicrobial peptides into therapeutically valuable anti-infective agents. Methods 42, 349–357 (2007).
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