Genome-scale RNAi screens for high-throughput phenotyping in bloodstream-form African trypanosomes-Reference-Cited by-同舟云学术

Genome-scale RNAi screens for high-throughput phenotyping in bloodstream-form African trypanosomes

Published:2014-12-11 Issue:1 Volume:10 Page:106-133
ISSN:1754-2189
Container-title:Nature Protocols
language:en
Short-container-title:Nat Protoc

Author:

Glover Lucy,Alsford Sam^ORCID,Baker Nicola,Turner Daniel J,Sanchez-Flores Alejandro,Hutchinson Sebastian,Hertz-Fowler Christiane,Berriman Matthew^ORCID,Horn David

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology

Link

https://www.nature.com/articles/nprot.2015.005.pdf

Reference48 articles.

1. Alsford, S. et al. High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome. Genome Res. 21, 915–924 (2011).

2. Alsford, S. et al. High-throughput decoding of antitrypanosomal drug efficacy and resistance. Nature 482, 232–236 (2012).

3. Baker, N., Alsford, S. & Horn, D. Genome-wide RNAi screens in African trypanosomes identify the nifurtimox activator NTR and the eflornithine transporter AAT6. Mol. Biochem. Parasitol. 176, 55–57 (2011).

4. Schumann Burkard, G., Jutzi, P. & Roditi, I. Genome-wide RNAi screens in bloodstream form trypanosomes identify drug transporters. Mol. Biochem. Parasitol. 175, 91–94 (2011).

5. Schumann Burkard, G. et al. Nucleolar proteins regulate stage-specific gene expression and ribosomal RNA maturation in Trypanosoma brucei. Mol. Microbiol. 88, 827–840 (2013).

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