Genome-wide RNAi screens in African trypanosomes identify the nifurtimox activator NTR and the eflornithine transporter AAT6
Author:
Funder
Bloomsbury colleges PhD studentship
Wellcome Trust
Publisher
Elsevier BV
Subject
Molecular Biology,Parasitology
Reference18 articles.
1. Trypanocidal drugs: mechanisms, resistance and new targets;Wilkinson;Expert Rev Mol Med,2009
2. Difluoromethylornithine for arseno-resistant Trypanosoma brucei gambiense sleeping sickness;Pepin;Lancet,1987
3. Nifurtimox–eflornithine combination therapy for second-stage African Trypanosoma brucei gambiense trypanosomiasis: a multicentre, randomised, phase III, non-inferiority trial;Priotto;Lancet,2009
4. A mechanism for cross-resistance to nifurtimox and benznidazole in trypanosomes;Wilkinson;Proc Natl Acad Sci U S A,2008
5. Genome-wide RNAi screens in bloodstream form trypanosomes identify drug transporters;Schumann Burkard;Mol Biochem Parasitol,2011
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