Measurement of drug-target engagement in live cells by two-photon fluorescence anisotropy imaging-Reference-Cited by-同舟云学术

Measurement of drug-target engagement in live cells by two-photon fluorescence anisotropy imaging

Published:2017-06-29 Issue:7 Volume:12 Page:1472-1497
ISSN:1754-2189
Container-title:Nature Protocols
language:en
Short-container-title:Nat Protoc

Author:

Vinegoni Claudio,Fumene Feruglio Paolo,Brand Christian,Lee Sungon,Nibbs Antoinette E,Stapleton Shawn,Shah Sunil,Gryczynski Ignacy,Reiner Thomas,Mazitschek Ralph,Weissleder Ralph

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology

Link

http://www.nature.com/articles/nprot.2017.043.pdf

Reference83 articles.

1. Vinegoni, C. et al. Advances in measuring single-cell pharmacokinetics and pharmacology in vivo. Drug Discov. Today 20, 1087–1092 (2015).

2. Miller, M.A. et al. Predicting therapeutic nanomedicine efficacy using a companion magnetic resonance imaging nanoparticle. Sci. Transl. Med. 7, 314 (2015).

3. Laughney, A.M. et al. Single-cell pharmacokinetic imaging reveals a therapeutic strategy to overcome drug resistance to the microtubule inhibitor eribulin. Sci. Transl. Med. 6, 261 (2014).

4. Dubach, J.M. et al. In vivo imaging of specific drug-target binding at subcellular resolution. Nat. Commun. 5, 3946 (2014).

5. Molina, D.M. et al. Monitoring drug target engagement in cells and tissues using the cellular thermal shift assay. Science 341, 84–87 (2013).

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