Effect of the meropenem MIC on the killing activity of meropenem and polymyxin B in combination against KPC-producing Klebsiella pneumoniae
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology
Link
https://www.nature.com/articles/ja201773.pdf
Reference17 articles.
1. Paul, M. et al. Combination therapy for carbapenem-resistant gram-negative bacteria. J. Antimicrob. Chemother. 69, 2305–2309 (2014).
2. Daikos, G. L. et al. Carbapenemase-producing Klebsiella pneumoniae bloodstream infections: lowering mortality by antibiotic combination schemes and the role of carbapenems. Antimicrob. Agents Chemother. 58, 2322–2328 (2014).
3. Qureshi, Z. A. et al. Treatment outcome of bacteremia due to KPC-producing Klebsiella pneumoniae: superiority of combination antimicrobial regimens. Antimicrob. Agents Chemother. 56, 2108–2113 (2012).
4. Tumbarello, M. et al. Predictors of mortality in bloodstream infections caused by Klebsiella pneumoniae carbapenemase-producing K. pneumoniae: importance of combination therapy. Clin. Infect. Dis. 55, 943–950 (2012).
5. Kitchel, B. et al. Genetic factors associated with elevated carbapenem resistance in KPC-producing Klebsiella pneumoniae. Antimicrob. Agents Chemother. 54, 4201–4207 (2010).
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