In vitro activity of polymyxin B in combination with meropenem, amikacin and gentamicin against Klebsiella pneumoniae clinical isolates co-harbouring aminoglycoside-modifying enzymes, blaNDM-1 and blaKPC-2

Author:

Firmo Elza Ferreira,Oliveira Júnior Jorge Belém,Scavuzzi Alexsandra Maria Lima,Alves Luis Carlos,Brayner Fábio André,Veras Dyana Leal,Lopes Ana Catarina de Souza

Funder

Programa de Pesquisa para o SUS (PPSUS) - Ministério da Saúde – Fundação de Amparo à Ciência e Tecnologia do Estado de Pernambuc

Publisher

Elsevier BV

Subject

Microbiology (medical),Immunology,Immunology and Allergy,Microbiology

Reference18 articles.

1. Association of blaNDM-1 with blaKPC-2 and aminoglycoside-modifying enzyme genes among Klebsiella pneumoniae, Proteus mirabilis and Serratia marcescens clinical isolates in Brazil;Firmo;J Global Antimicrob Resist,2019

2. Unusual association of NDM-1 with KPC-2 and armA among Brazilian Enterobacteriaceae isolates;Quiles;Braz J Med Biol Res,2015

3. Emergence of Klebsiella pneumoniae isolate co-producing NDM-1 with KPC-2 from India;Kumarasamy;J Antimicrob Chemother,2012

4. Antimicrobial resistance: impact on clinical and economic outcomes and the need for new antimicrobials;Thabit;Expert Opin Pharmacother,2015

5. Evaluation of activity and emergence of resistance of polymyxin B and ZTI-01 (fosfomycin for injection) against KPC-producing Klebsiella pneumoniae;Diep;Antimicrob Agents Chemother,2018

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