Multiplexing molecular tension sensors reveals piconewton force gradient across talin-1
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology,Biochemistry,Biotechnology
Link
http://www.nature.com/articles/nmeth.4431.pdf
Reference46 articles.
1. Petridou, N.I., Spiró, Z. & Heisenberg, C.P. Multiscale force sensing in development. Nat. Cell Biol. 19, 581–588 (2017).
2. Vogel, V. & Sheetz, M. Local force and geometry sensing regulate cell functions. Nat. Rev. Mol. Cell Biol. 7, 265–275 (2006).
3. Gordon, W.R. et al. Mechanical allostery: evidence for a force requirement in the proteolytic activation of notch. Dev. Cell 33, 729–736 (2015).
4. Rognoni, L., Stigler, J., Pelz, B., Ylänne, J. & Rief, M. Dynamic force sensing of filamin revealed in single-molecule experiments. Proc. Natl. Acad. Sci. USA 109, 19679–19684 (2012).
5. del Rio, A. et al. Stretching single talin rod molecules activates vinculin binding. Science 323, 638–641 (2009).
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