Division of labor by dual feedback regulators controls JAK2/STAT5 signaling over broad ligand range

Author:

Bachmann Julie1,Raue Andreas23,Schilling Marcel1,Böhm Martin E4,Kreutz Clemens23,Kaschek Daniel2,Busch Hauke3,Gretz Norbert5,Lehmann Wolf D4,Timmer Jens236,Klingmüller Ursula1

Affiliation:

1. Division of Systems Biology of Signal Transduction, DKFZ‐ZMBH Alliance, German Cancer Research Center Heidelberg Germany

2. Center for Biological Signaling Studies (BIOSS), Physikalisches Institut, University of Freiburg Freiburg Germany

3. Freiburg Institute for Advanced Studies (FRIAS) and Zentrum für Biosystemanalyse (ZBSA), University of Freiburg Freiburg Germany

4. Molecular Structure Analysis, German Cancer Research Center Heidelberg Germany

5. Medical Research Center, Medical Faculty Mannheim, University of Heidelberg Mannheim Germany

6. Department of Clinical and Experimental Medicine, Linköping University Linköping Sweden

Publisher

EMBO

Subject

Applied Mathematics,Computational Theory and Mathematics,General Agricultural and Biological Sciences,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Information Systems

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