Multiple roles of mucins in pancreatic cancer, a lethal and challenging malignancy

Author:

Moniaux N,Andrianifahanana M,Brand R E,Batra S K

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Reference48 articles.

1. Adsay NV, Merati K, Andea A, Sarkar F, Hruban RH, Wilentz RE, Goggins M, Iocobuzio-Donahue C, Longnecker DS, Klimstra DS (2002) The dichotomy in the preinvasive neoplasia to invasive carcinoma sequence in the pancreas: differential expression of MUC1 and MUC2 supports the existence of two separate pathways of carcinogenesis. Mod Pathol 15: 1087–1095

2. Andrianifahanana M, Moniaux N, Schmied BM, Ringel J, Friess H, Hollingsworth MA, Buchler MW, Aubert JP, Batra SK (2001) Mucin (MUC) gene expression in human pancreatic adenocarcinoma and chronic pancreatitis: a potential role of MUC4 as a tumor marker of diagnostic significance. Clin Cancer Res 7: 4033–4040

3. Andrianifahanana M, Moniaux N, Batra SK (2004) Pathophysiological perspectives of pancreatic mucins. In Toxicology of the Pancreas – Biology, Pathophysiology, Etiology and Molecular Biology of Pancreatic Injury Pour P (ed) London, UK: Taylor & Francis, In press

4. Balague C, Gambus G, Carrato C, Porchet N, Aubert JP, Kim YS, Real FX (1994) Altered expression of MUC2, MUC4, and MUC5 mucin genes in pancreas tissues and cancer cell lines. Gastroenterology 106: 1054–1061

5. Braga VM, Pemberton LF, Duhig T, Gendler SJ (1992) Spatial and temporal expression of an epithelial mucin, Muc-1, during mouse development. Development 115: 427–437

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