Improved total synthesis of incednam-Reference-Cited by-同舟云学术

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Improved total synthesis of incednam

Published:2013-02-06 Issue:3 Volume:66 Page:155-159
ISSN:0021-8820
Container-title:The Journal of Antibiotics
language:en
Short-container-title:J Antibiot

Author:

Takada Akira,Uda Kanjiro,Ohtani Takashi,Tsukamoto Shinya,Takahashi Daisuke,Toshima Kazunobu

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Pharmacology

Link

http://www.nature.com/articles/ja20134.pdf

Reference20 articles.

1. Futamura, Y. et al. Discovery of incednine as a potent modulator of the anti-apoptotic function of Bcl-xL from microbial origin. J. Am. Chem. Soc. 130, 1822–1823 (2008).

2. Tsujimoto, Y., Finger, L. R., Yunis, J., Nowell, P. C. & Croce, C. M. Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation. Science 226, 1097–1099 (1984).

3. Reed, J. C., Cuddy, M., Slabiak, T., Croce, C. M. & Nowell, P. C. Oncogenic potential of bcl-2 demonstrated by gene transfer. Nature 336, 259–261 (1988).

4. Gross, A., McDonnell, J. M. & Korsmeyer, S. J. BCL-2 family members and the mitochondria in apoptosis. Genes Dev. 13, 1899–1911 (1999).

5. Ohtani, T. et al. Total synthesis of incednam, the aglycon of incednine. Org. Lett. 12, 5068–5071 (2010).

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